학술논문
Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis.
Document Type
Article
Author
Source
Subject
*ANKYLOSING spondylitis
*PREGABALIN
*INFLAMMATION
*BACKACHE
*OPIOIDS
*DRUG therapy
*DRUG administration
*DRUG dosage
*DISEASE progression
*PATIENTS
*THERAPEUTICS
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Language
ISSN
2090-682X
Abstract
Background.Ankylosing spondylitis (AS) is a systemic inflammatory diseasewith chronic back pain as themost common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment. [ABSTRACT FROM AUTHOR]