학술논문
Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumors.
Document Type
Article
Author
Source
Subject
*ACETYLTRANSFERASES
*GENETIC mutation
*EPITHELIAL cells
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*
Language
ISSN
0007-0920
Abstract
Investigates the histone acetyltransferases CBP and PCAF for mutations in human epithelial cell lines and primary tumors. Identification of two CBP truncations, seven PCAF missense variants and four CBP intronic microdeletions; Rare inactivating mutations in cancer cell lines.