학술논문
The concentration of serum zinc in celiac patients compared to healthy subjects in Tehran.
Document Type
Article
Author
Source
Subject
*CELIAC disease diagnosis
*CELIAC disease treatment
*THERAPEUTIC use of zinc
*ANALYSIS of variance
*CELIAC disease
*CHI-squared test
*GASTROENTEROLOGY
*INTESTINAL absorption
*MEDICAL care
*EVALUATION of medical care
*METABOLISM
*NUTRITIONAL requirements
*PATIENTS
*TUMOR markers
*ZINC
*DATA analysis
*CONTROL groups
*DESCRIPTIVE statistics
*SYMPTOMS
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Language
ISSN
2008-2258
Abstract
Aim: This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. Background: Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions. Patients and methods: Sera of 30 celiac cases and 30 healthy normal cohorts as control group were obtained. Atomic absorption spectrophotometer was employed for estimating serum zinc level. Results: Zinc concentrations in patients diagnosed with CD were significantly lower than healthy subjects (75.97±12 compared with 92.83±18, P-value < 0.0001). Conclusion: The result of this study shows that serum zinc concentration is decreased in celiac patients compare to healthy controls. Serum zinc may thus be a marker of CD in adults presenting with gastrointestinal symptoms. [ABSTRACT FROM AUTHOR]