학술논문
Structural organization of viral RNA-dependent RNA polymerases.
Document Type
Article
Author
Source
Subject
*RNA polymerases
*VIRAL proteins
*PICORNAVIRUSES
*CALICIVIRUSES
*X-ray spectra
*FLAVIVIRUSES
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*
*
*
*
Language
ISSN
0006-2979
Abstract
This review describes available data on the structure of viral RNA-dependent RNA polymerases (RdRP) obtained from X-ray analysis and discusses the functional significance of the structural elements of these enzymes. Because most of the studies done to date relate to RdRP structures of picorna-, flavi-, and caliciviruses, here we consider mostly the structures of RdRP of these groups of viruses, and also include information about polymerases of other virus families. [ABSTRACT FROM AUTHOR]