학술논문

Gluten related disorders.
Document Type
Article
Source
Gastroenterology & Hepatology from Bed to Bench. Apr2012 Supplement 1, Vol. 5, pS1-S7. 7p.
Subject
*AUTOIMMUNE disease diagnosis
*CELIAC disease diagnosis
*SMALL intestine
*CELIAC disease
*GENETICS
*GLUTEN
*GLUTEN-free diet
*IMMUNITY
*HLA-B27 antigen
*ANATOMY
Language
ISSN
2008-2258
Abstract
Gluten associated disorders and the question around these associations has recently attracted attentions of many health professionals. This is because of high prevalence of undiagnosed gluten related disorders presenting with a multitude of symptoms and complications inside and outside small bowel. While the environmental factors associated with a complex genetics are leading to destructions of the small intestinal villi resulting in malabsorption syndrome in CD, GS is characterised by negative antibodies and grossly normal histology. The association between celiac disease and other disorders has been clearly established and there have been many reports of numerous intestinal and extra intestinal coexistent disorders with CD. But there is little information available regarding the clinical behavior of gluten sensitivity. In this review we discuss the clinical presentation of non-celiac GS and the prospect of current and the future diagnostic pathway. [ABSTRACT FROM AUTHOR]