학술논문
Impact of vaccination against Haemophilus influenzae type b with and without a booster dose on meningitis in four South American countries
Document Type
Article
Author
Garcia, Salvador; Lagos, Rosanna; Muñoz, Alma; Picón, Teresa; Rosa, Raquel; Alfonso, Adriana; Abriata, Graciela; Gentile, Angela; Romanin, Viviana; Regueira, Mabel; Chiavetta, Laura; Agudelo, Clara Inés; Castañeda, Elizabeth; De la Hoz, Fernando; Higuera, Ana Betty; Arce, Patricia; Cohen, Adam L.; Verani, Jennifer; Zuber, Patrick; Gabastou, Jean-Marc
Source
Subject
*HAEMOPHILUS influenzae
*MENINGITIS
*DRUG dosage
*IMMUNIZATION
*DISEASE incidence
*VACCINATION
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Language
ISSN
0264-410X
Abstract
Abstract: To inform World Health Organization recommendations regarding use of Haemophilus influenzae type b (Hib) vaccines in national immunization programs, a multi-country evaluation of trends in Hib meningitis incidence and prevalence of nasopharyngeal Hib carriage was conducted in four South American countries using either a primary, three-dose immunization schedule without a booster dose or with a booster dose in the second year of life. Surveillance data suggest that high coverage of Hib conjugate vaccine sustained low incidence of Hib meningitis and low prevalence of Hib carriage whether or not a booster dose was used. [Copyright &y& Elsevier]