학술논문
Pharmacokinetics and protein binding of linezolid in cerebrospinal fluid and serum in a case of post-neurosurgical bacterial meningitis.
Document Type
Article
Author
Source
Subject
*DRUG therapy
*ANTI-infective agents
*BACTERIAL diseases
*HIGH performance liquid chromatography
*MENINGITIS
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Language
ISSN
0036-5548
Abstract
We describe a case of bacterial meningitis in a patient administered linezolid (LZD). The ratio of free to total LZD concentrations in cerebrospinal fluid (CSF) was 1 for all measurements, and the LZD concentration in CSF measured at the trough level was almost the same as the free serum concentration. [ABSTRACT FROM AUTHOR]