학술논문
Long-Term Cultured Human Skin Mast Cells Are Suitable for Pharmacological Studies of Anti-Allergic Drugs Due to High Responsiveness to EcεRI Cross-Linking.
Document Type
Article
Source
Subject
*SKIN
*MAST cells
*ANTIALLERGIC agents
*CROSSLINKING (Polymerization)
*CELL receptors
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Language
ISSN
0916-8451
Abstract
The article discusses a study which examines the applicability of human skin mast cells (skMCs) for pharmacological studies of anti-allergic drugs. Findings of the study reveal that long-term skMCs demonstrated profound responsiveness towards high affinity IgE receptor cross-linking. It concludes that skMCs can be useful in pre-clinical testing of anti-allergic agents.