부산대학교 도서관

Precisely controlled conditions of acylation and 2′,3′-O-isomerization allowed to synthesize tripivaloyl derivatives of cytidine with free 2′- or 3′-hydroxyl group in a simple manner. Acylation of 2′-C-β-methylcytidine proceeded in a different way and resulted in the formation of tripivaloyl 2'-hydroxy nucleoside, or dipivaloyl 2′,3′-dihydroxy compound. All these products may be applied as key intermediates in the regioselective modification of 2′,3′-cis-diol system. [ABSTRACT FROM AUTHOR]