학술논문

Route of delivery and baseline left ventricular ejection fraction, key factors of bone-marrow-derived cell therapy for ischaemic heart disease.
Document Type
Article
Source
European Journal of Heart Failure. Sep2009, Vol. 11 Issue 9, p887-896. 10p. 6 Diagrams, 2 Charts.
Subject
*BONE marrow
*CELLULAR therapy
*STEM cells
*HEART diseases
*MYOCARDIAL infarction
Language
ISSN
1388-9842
Abstract
Aims: Previous evaluation of autologous bone-marrow stem-cell (BMSC) therapy following acute myocardial infarction (AMI) suggests that cell dose and timing of stem-cell administration post-MI are important factors in the efficacy of cellular therapy. This study aimed to assess whether route of delivery and baseline left ventricular ejection fraction (LVEF) of the participants may also affect the outcome of BMSC treatment in patients with AMI and ischaemic heart disease (IHD). [ABSTRACT FROM PUBLISHER]