학술논문
DSC analysis of human fat tissue in idiopathic avascular necrosis of the femoral head.
Document Type
Article
Author
Source
Subject
*GAS chromatography
*FATTY acids
*IDIOPATHIC femoral necrosis
*OSTEONECROSIS
*MIDDLE-aged persons
*ADIPOSE tissues
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Language
ISSN
1388-6150
Abstract
Avascular necrosis of human femoral head (ANFH) causes incongruity in the joint that leads to disability in patients requires total hip arthroplasty (THA). Several etiological factors of ANFH have been proposed in the literature but there are cases of idiopathic origin. We observed macroscopic variation in quality of the subcutaneous fat tissue in patients with ANFH compared to patients with osteoarthritis or hip fracture during THA procedures. The samples were analysed by histology, gas chromatography (GC) and differential scanning calorimetry (DSC). Conclusion: the alteration in the fatty acid profile did not cause histological changes, however we could detect biochemical changes using DSC and GC. [ABSTRACT FROM AUTHOR]