학술논문

Long-Term Preservation of Vision in Progressive Outer Retinal Necrosis Treated with Combination Antiviral Drugs and Highly Active Antiretroviral Therapy.
Document Type
Article
Source
Ocular Immunology & Inflammation. Dec2007, Vol. 15 Issue 6, p425-427. 3p. 3 Black and White Photographs.
Subject
*MEDICAL research
*RETINAL diseases
*NECROSIS
*ANTIVIRAL agents
*THERAPEUTICS
Language
ISSN
0927-3948
Abstract
Purpose: To report the successful long-term treatment of varicella zoster virus-associated progressive outer retinal necrosis (VZV-PORN) with aggressive antiviral combination drugs along with highly active antiretroviral therapy (HAART). Design: Interventional case report. Methods: Combined treatment of progressive outer retinal necrosis in a university-based tertiary eye hospital with ganciclovir implant, intravenous acyclovir (10 mg/kg every 8 h), intravitreal foscarnet (2.4 mg), and HAART. Results: Successful treatment of progressive outer retinal necrosis with disease remission and preservation of 20/20 visual acuity out to 1 year. Conclusions: Combination antiviral therapy and HAART may improve long-term visual outcomes for VZV-PORN. [ABSTRACT FROM AUTHOR]