부산대학교 도서관

Objective: The aim of our retrospective study was to evaluate early and midterm clinical outcomes of two surgical techniques: open anastomosis in deep hypothermic circulatory arrest (DHCA) compared to anastomosis with clamped aorta while continuing on extracorporeal circulation (CECC). Methods: Between November 1997 and February 2002, 67 patients were operated for acute type A aortic dissection. Records of 35 patients with isolated replacement of the ascending aorta without intervention on the aortic arch were retrospectively reviewed. The influence of two techniques (DHCA n = 15, CECC n = 20) on clinical outcome and midterm follow up was investigated. Results: There were no statistically significant differences in preoperative data. Female gender in the DHCA group was coincidentally more frequent. Intraoperative management did not result in different early clinical outcome. 30-day mortality was not statistically different. Mean follow up time was 20.7 ± 11.1 months in the DHCA group and 28.7 ± 14.3 months in the CECC group. One-year and 3-year survival estimates in DHCA group were 85%± 7% and 79%± 9%, respectively. In the CECC group similar survivals were 80%± 10% and 73%± 11%, respectively. No statistically significant differences between the two groups were obtained in early or midterm outcome. Conclusion: While there is no difference in clinical outcome in surgical treatment of acute type A aortic dissection with or without circulatory arrest, there are some practical technical advantages if the distal anastomosis is performed in an open manner. Probably the long-term outcome too is better with this anastomosis technique. [ABSTRACT FROM AUTHOR]