학술논문
Neurologic toxicity associated with interferon α therapy for renal cell carcinoma.
Document Type
Article
Author
Source
Subject
*RENAL cell carcinoma
*INTERFERONS
*METASTASIS
*NEUROTOXICOLOGY
*ANTINEOPLASTIC agents
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Language
ISSN
0919-8172
Abstract
A 67-year-old man received interferon α (IFN α) therapy for lung metastases of renal cell carcinoma (RCC). Multiple pulmonary metastases disappeared completely. However, neurological toxicity was detected by magnetic resonance imaging (MRI) as abnormal brain lesions. After discontinuation of IFN α therapy, his neurological symptoms and abnormal lesions on MRI disappeared completely. Complete remission of RCC has continued, and results of neurological study have remained normal for 5 years after discontinuation of IFN α therapy. [ABSTRACT FROM AUTHOR]