학술논문

Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5.
Document Type
Article
Source
Psychopharmacology. Feb2006, Vol. 184 Issue 3/4, p401-408. 8p. 2 Charts, 5 Graphs.
Subject
*NICOTINE
*ENZYMES
*PROTEINS
*NICOTINE addiction
*LABORATORY mice
Language
ISSN
0033-3158
Abstract
The article discusses research on the association of nicotine self-administration in mice with rates of nicotine inactivation by CYP2A5 homologue. The mice propagated from high and low nicotine consuming mice were analyzed for CYP2A5 hepatic protein levels and in vitro nicotine metabolizing activity.