학술논문
The Enterics for Global Health (EFGH) Shigella Surveillance Study in The Gambia.
Document Type
Article
Author
Conteh, Bakary; Badji, Henry; Jallow, Abdoulie F; Karim, Mehrab; Manneh, Alhagie; Keita, Belali; Sarwar, Golam; Ceesay, Bubacarr E; Jarju, Sheikh; Jabang, Abdoulie M J; Baldeh, Ebrima; Ikumapayi, Usman N; Secka, Ousman; Antonio, Martin; Roca, Anna; D'Alessandro, Umberto; Kotloff, Karen L; Hossain, M Jahangir
Source
Subject
*SHIGELLOSIS
*SHIGELLA
*WORLD health
*VACCINE trials
*WATERSHEDS
*PSYCHOLOGY of the sick
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Language
ISSN
2328-8957
Abstract
Background The Gambia, located in West Africa, is one of 7 country sites conducting the Enterics for Global Health (EFGH) Shigella Surveillance Study to establish incidence and consequence of Shigella -associated medically attended diarrhea among children 6–35 months old. Methods Here we describe the study site and research experience, sociodemographic characteristics of the study catchment area, facilities of recruitment for diarrhea case surveillance, and known care-seeking behavior for diarrheal illness. We also describe The Gambia's healthcare system and financing, current vaccine schedule and Shigella vaccine adaptation, local diarrhea management guidelines and challenges, and antibiotic resistance patterns in the region. Conclusions The EFGH study in The Gambia will contribute to the multisite network of Shigella surveillance study and prepare the site for future vaccine trials. In addition, the data produced will inform policy makers about prevention strategies and upcoming Shigella vaccine studies among children in this setting. [ABSTRACT FROM AUTHOR]