학술논문
Impact of dementia on 30-, 180-, and 365-day mortality during the first pandemic wave in older adults seen in spanish emergency departments diagnosed with or without COVID-19.
Document Type
Article
Author
Fernández Alonso, Cesáreo; Fuentes Ferrer, Manuel E.; García-Lamberechts, Eric Jorge; Aguiló Mir, Sira; Jiménez, Sònia; Jacob, Javier; Piñera Salmerón, Pascual; Gil-Rodrigo, Adriana; Llorens, Pere; Burillo-Putze, Guillermo; Alquezar-Arbé, Aitor; Bretones Baena, Sierra; Fernández Cardona, María; Hernández González, Rocío; Moreno Martín, Miguel; Barnes Parra, Ana; El Farh, Imane; Valle Borrego, Beatriz; Quero Motto, Eva; Artieda Larrañaga, Alberto
Source
Subject
Language
ISSN
1360-7863
Abstract
AbstractObjectivesMethodResultsConclusionTo assess whether dementia is an independent predictor of death after a hospital emergency department (ED) visit by older adults with or without a COVID-19 diagnosis during the first pandemic wave.We used data from the EDEN-Covid (Emergency Department and Elderly Needs during Covid) cohort formed by all patients ≥65 years seen in 52 Spanish EDs from March 30 to April 5, 2020. The association of prior history of dementia with mortality at 30, 180 and 365 d was evaluated in the overall sample and according to a COVID-19 or non COVID diagnosis.We included 9,770 patients aged 78.7 ± 8.3 years, 51.1% men, 1513 (15.5%) subjects with prior history of dementia and 3055 (31.3%) with COVID-19 diagnosis. 1399 patients (14.3%) died at 30 d, 2008 (20.6%) at 180 days and 2456 (25.1%) at 365 d. The adjusted Hazard Ratio (aHR) for age, sex, comorbidity, disability and diagnosis for death associated with dementia were 1.16 (95% CI 1.01–1.34) at 30 d; 1.15 at 180 d (95% CI 1.03–1.30) and 1.19 at 365 d (95% CI 1.07–1.32), p < .001. In patients with COVID-19, the aHR were 1.26 (95% CI: 1.04–1.52) at 30 days; 1.29 at 180 d (95% CI: 1.09–1.53) and 1.35 at 365 d (95% CI: 1.15–1.58).Dementia in older adults attending Spanish EDs during the first pandemic wave was independently associated with 30-, 180- and 365-day mortality. This impact was lower when adjusted for age, sex, comorbidity and disability, and was greater in patients diagnosed with COVID-19. [ABSTRACT FROM AUTHOR]