학술논문
Clinical impacts of the rapid diagnostic method on positive blood cultures.
Document Type
Article
Source
Subject
*BLOOD
*T-test (Statistics)
*FISHER exact test
*RAPID diagnostic tests
*DESCRIPTIVE statistics
*RETROSPECTIVE studies
*MANN Whitney U Test
*CHI-squared test
*CAUSES of death
*CELL culture
*MEDICAL records
*ACQUISITION of data
*RESEARCH methodology
*HEALTH outcome assessment
*DATA analysis software
*LENGTH of stay in hospitals
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Language
ISSN
0007-5027
Abstract
Objective This study aimed to evaluate the impact of short-term incubation (STI) protocol on clinical outcomes of bloodstream infection (BSI) patients. Methods A total of 1363 positive blood culture records from January 2019 to December 2021 were included. The main clinical outcomes included pathogen identification turnaround time (TAT), antimicrobial susceptibility testing (AST) TAT, and length of total hospital stay. Results The TAT of pathogen identification and AST significantly decreased after implementing the STI protocol (2.2 vs 1.4 days and 3.4 vs 2.5 days, respectively, with P <.001 for both). Moreover, for patients with Gram-negative bacteria (GNB)–infected BSIs, the length of total hospital stay decreased from 31.9 days to 27.1 days, indicating that these patients could be discharged 5 days earlier after implementing the STI protocol (P <.01). Conclusion The protocol led to a significant reduction in TAT and improved clinical outcomes, particularly for GNB organisms. The findings suggest that the STI protocol can improve patient outcomes and hospital resource utilization in the management of BSIs. [ABSTRACT FROM AUTHOR]