학술논문
Cardiovascular Biomarkers in Cardio-Oncology: Antineoplastic Drug Cardiotoxicity and Beyond.
Document Type
Article
Author
Attanasio, Umberto; Di Sarro, Elena; Tricarico, Lucia; Di Lisi, Daniela; Armentaro, Giuseppe; Miceli, Sofia; Fioretti, Francesco; Deidda, Martino; Correale, Michele; Novo, Giuseppina; Sciacqua, Angela; Nodari, Savina; Cadeddu, Christian; Tocchetti, Carlo Gabriele; Palazzuoli, Alberto; Mercurio, Valentina
Source
Subject
*CARDIOTOXICITY
*ANTINEOPLASTIC agents
*TUMOR markers
*CARDIO-oncology
*LITERATURE reviews
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Language
ISSN
2218-273X
Abstract
Serum biomarkers represent a reproducible, sensitive, minimally invasive and inexpensive method to explore possible adverse cardiovascular effects of antineoplastic treatments. They are useful tools in risk stratification, the early detection of cardiotoxicity and the follow-up and prognostic assessment of cancer patients. In this literature review, we aim at describing the current state of knowledge on the meaning and the usefulness of cardiovascular biomarkers in patients with cancer; analyzing the intricate relationship between cancer and cardiovascular disease (especially HF) and how this affects cardiovascular and tumor biomarkers; exploring the role of cardiovascular biomarkers in the risk stratification and in the identification of chemotherapy-induced cardiotoxicity; and providing a summary of the novel potential biomarkers in this clinical setting. [ABSTRACT FROM AUTHOR]