학술논문

Recurrent upper respiratory tract infections in early childhood: a newly defined clinical condition.
Document Type
Article
Source
Italian Journal of Pediatrics. 2/16/2024, Vol. 50 Issue 1, p1-5. 5p.
Subject
*CONFIDENCE intervals
*SCIENTIFIC observation
*RESPIRATORY infections
*FISHER exact test
*DISEASE relapse
*RISK assessment
*RESEARCH funding
*DESCRIPTIVE statistics
*CHI-squared test
*DATA analysis software
*ODDS ratio
*STATISTICAL sampling
*LONGITUDINAL method
*DISEASE risk factors
*CHILDREN
Language
ISSN
1720-8424
Abstract
Background: Recurrent Upper Respiratory Tract Infections (R-URTIs) pose a significant challenge in pediatric healthcare, affecting both children and their families. This study aimed to investigate the prevalence, risk factors, and clinical implications of R-URTI in children aged 0–5 years. Methods: This observational study involved a sample of 483 children aged 0–5 years, focusing on establishing a practical and dynamic definition of R-URTI. Family pediatricians prospectively collected socio-demographic information, medical history, and recorded the occurrence of URTI episodes. Children were followed from recruitment until March 2021, predating the COVID-19 outbreak. Results: A substantial prevalence of R-URTIs was found, estimating it at 5–10% among this age group. To define R-URTI, a practical and dynamic criterion was proposed: children experiencing a minimum of four URTI episodes, each lasting four days or more, within a six-month period, with intervals of well-being in between. Conclusions: The study highlighted that specific risk factors for R-URTI were elusive, suggesting that this condition may affect children regardless of their family or clinical history. Moreover, the study's stratification by age group and times of observation facilitated patient-specific clinical decision-making. The proposed definition may represent a valuable tool for clinicians in diagnosing and addressing R-URTI cases. [ABSTRACT FROM AUTHOR]