학술논문
Emerging Roles of (1→3)-β-D-Glucan in Cerebrospinal Fluid for Detection and Therapeutic Monitoring of Invasive Fungal Diseases of the Central Nervous System.
Document Type
Article
Author
Source
Subject
*ASPERGILLOSIS diagnosis
*BIOMARKERS
*ANTIFUNGAL agents
*DRUG efficacy
*BETA-glucans
*MYCOSES
*SENSITIVITY & specificity (Statistics)
*FUNGAL meningitis
*EVALUATION
CENTRAL nervous system infections
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Language
ISSN
1058-4838
Abstract
The article discusses a study by J. Bigot and colleagues on β-D-glucan in the cerebrospinal fluid (CSF) as a biomarker for the diagnosis of hematogenous Candida meningoencephalitis (HCME) and mold infections of the central nervous system (CNS). Topics include potential clinical utility of β-D-glucan and other polysaccharides, factors associated with mold infections of the CNS, and difficulty of diagnosing mucormycosis, which causes devastating damage to the CNS.