부산대학교 도서관

Atherosclerotic Cardiovascular Disease (ASCVD) is a globally prevalent non-communicable disease contributing significantly to Cardiovascular (CV) morbidity and mortality. Approximately, 70% of Cardiovascular Disease (CVD) cases and deaths have been attributed to modifiable risk factors. To overcome the risk factors, therapeutic adherence plays a pivotal role in ASCVD management and is determined by multiple factors. This review highlights the effect of poor adherence on ASCVD events in India, ways to prevent non-adherence and ensure optimum outcomes for patients. Among the major risk factors that cause ASCVD, dyslipidemia is often neglected or inadequately treated. Studies from India have identified varying rates of adherence to lipid lowering therapies in ASCVD. Factors such as lower socioeconomic status, health literacy, asymptomatic nature of disease, forgetfulness and cost of medications contribute towards non-adherence. This has resulted in significantly higher hospitalizations for CVDs and an increased risk of mortality and indirect cost. Further, emphasis is warranted on patient education, enhanced physician-patient relationship and communication, increased access to health care, frequent use of fixed drug combinations, and affordability in improving therapeutic adherence in ASCVD. With innovation in therapeutics, the pharmaceutical sector can contribute significantly to improve adherence. [ABSTRACT FROM AUTHOR]