학술논문

Luminescent DNA-origami nano-rods dispersed in a lyotropic chromonic liquid crystal.
Document Type
Article
Source
Liquid Crystals. May2023, Vol. 50 Issue 7-10, p1243-1251. 9p.
Subject
*LYOTROPIC liquid crystals
*POLYMER liquid crystals
*CRYSTAL defects
*LIQUID crystals
*CROMOLYN sodium
*DNA folding
Language
ISSN
0267-8292
Abstract
Anisometric DNA nanoparticles with precisely tailored size and shape are prepared by three-dimensional folding of DNA – DNA origami – marked with a fluorescent intercalating dye (YOYO-1), stabilised with silica, and dispersed in a lyotropic chromonic liquid crystal (an aqueous solution of disodium cromoglycate). Observations by total internal reflection fluorescence microscopy indicate that the luminescent nanoparticles are stable in the liquid crystal dispersion and accumulate at the positions of point defects in the liquid crystal director field. The observations indicate that silica-stabilisation of the nanoparticles prevents the dye from leaking into the liquid crystal host and that the luminescent particles assemble at disclinations. [ABSTRACT FROM AUTHOR]