학술논문
Upper respiratory tract OC43 infection model for investigating airway immune-modifying therapies.
Document Type
Article
Author
Source
American Journal of Respiratory Cell & Molecular Biology; Dec2023, Vol. 69 Issue 6, pE1-15, 15p
Subject
Language
ISSN
10441549
Abstract
The article introduces an upper respiratory tract OC43 infection model for evaluating airway immune-modifying therapies, conducted on mice using OC43 viral challenges and various treatments. Topics include the experimental methods, viral challenge procedures, and comprehensive analyses encompassing nasal and bronchoalveolar lavage, histology, immunofluorescence, and immune transcriptome expression analysis.