부산대학교 도서관

Keywords: ARIA; Amyloid; Immunotherapy; Cerebrovasculature; Blood brain barrier; Perivascular macrophages; Microglia EN ARIA Amyloid Immunotherapy Cerebrovasculature Blood brain barrier Perivascular macrophages Microglia 1 3 3 11/03/23 20231020 NES 231020 Microhemorrhages as a consequence of anti-Ab immunotherapy were first identified over 20 years ago in a single page report in Science by Pfeifer et al. [[1]]. Abbreviations A Amyloid Beta AD Alzheimer's Disease ARIA Amyloid Related Imaging Abnormalities BMDM Bone Marrow Derived Macrophage CAA Cerebral Amyloid Angiopathy FDA Food and Drug Administration MMP Matrix Metalloproteinase Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. ARIA, Amyloid, Immunotherapy, Blood brain barrier, Cerebrovasculature, Microglia, Perivascular macrophages Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta. [Extracted from the article]