학술논문

Epstein–Barr virus infection leading to multiorgan involvement in an immunocompetent man.
Document Type
Case Study
Source
Clinical Case Reports. Oct2023, Vol. 11 Issue 10, p1-7. 7p.
Subject
*EPSTEIN-Barr virus diseases
*MONONUCLEOSIS
*VIRAL antigens
*EPSTEIN-Barr virus
*VIRAL antibodies
*INTESTINAL perforation
Language
ISSN
2050-0904
Abstract
Key Clinical Message: Epstein–Barr virus (EBV) is a commonly asymptomatic widespread human herpes virus affecting over 90% of the population. It mostly originates complications like simple sore throat and infectious mononucleosis but severe manifestations are rare. Herein we report a 30‐year‐old immunocompetent man who presented with fever, sore throat, general weakness, and drowsiness. The diagnosis was formulated based on the positive RT‐PCR test for EBV DNA and serological detection of IgM antibody against viral capsid antigen. The patient developed severe meningoencephalitis, myocarditis, and bowel perforation and passed away after 72 days of hospitalization. [ABSTRACT FROM AUTHOR]