학술논문

Digestive cancer surgery in low-mid income countries: analysis of postoperative mortality and complications in a single-center study.
Document Type
Article
Source
Langenbeck's Archives of Surgery. 10/21/2023, Vol. 408 Issue 1, p1-12. 12p.
Subject
*ONCOLOGIC surgery
*SURGICAL complications
*PREOPERATIVE risk factors
*CARCINOEMBRYONIC antigen
*SURGICAL excision
MORTALITY risk factors
Language
ISSN
1435-2443
Abstract
Purpose: This study aimed to analyze postoperative and 90-day morbidity and mortality and their risk factors in all digestive cancer curative intent resections of a single digestive surgical department in a low-mid income country. Methods: All consecutive patients who underwent a surgical resection for digestive cancer with a curative intent between January 1, 2021, and December 31, 2021, were included. This is a retrospective analysis of a prospective cancer surgery database managed during the period. Patterns and factors associated with increased morbidity and mortality were analyzed and presented in tabular and descriptive forms. Results: Seventy-six patients were included, 38 (50%) were men with a mean age of 59 years (±13.5). Forty patients (52.63%) had tumors locally advanced, staged CT3–CT4 on preoperative imagery. Thirty-three of our population (43.42%) had laparoscopic surgery (conversion rate at 12.12%). In immediate preoperative, the morbidity rate was 36.84%; among each, 7 patients (9.21%) had serious complications (>2 Clavien-Dindo grade), and mortality rate was 5.26%. At 90 days after surgery, morbidity remained the same, and mortality increased to 7.9%. Risk factors for increased morbidity and mortality were female gender, obesity, high levels of carcinoembryonic antigen, hypoalbuminemia, laparotomy approach, hand sewn anastomosis, prolonged operating time, and wide drainage (p < 0.05). Conclusions: This study provides figures on mortality and morbidity related to digestive cancer curative surgery in a low-mid income country digestive department and discusses risk factors increasing postoperative complications and death. [ABSTRACT FROM AUTHOR]