부산대학교 도서관

Keywords: Esophageal cancer; Adenocarcinoma; Lymphadenectomy EN Esophageal cancer Adenocarcinoma Lymphadenectomy 2202 2204 3 10/18/23 20231001 NES 231001 Introduction Esophageal cancer is a complex malignant disease process with early nodal dissemination due to the extensive esophageal submucosal lymphatic plexus.[1]-[3] Pattern of lymph node spread is unpredictable as evidenced by the discovery of skip metastases, where lymph nodes adjacent to the primary tumor are negative, while nodes more distant are positive.[4],[5] Consequently, surgical approaches to tumor resection and the extent of lymphadenectomy are debated.[1],[6] Our study focused on esophageal cancer patients who underwent three-field minimally invasive esophagectomy (MIE) with extended two-field lymphadenectomy. The ratio of infiltrated nodes to resected nodes was highest in the continuous metastasis group (44%), as compared to the gastric positive node group(14%) and skip metastasis group (10%) ( I p i < 0.001). Of the 82 patients with node positive disease on final pathology: 61 (74%) patients had contiguous positive gastric nodes, 5 (6%) had isolated positive thoracic nodes or skip metastasis, and 16 (20%) had both positive gastric and thoracic nodes or continuous metastasis. [Extracted from the article]