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Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.

Document Type

Article

Author

Sneyers, Flore; Kerkhofs, Martijn; Speelman-Rooms, Femke; Welkenhuyzen, Kirsten; La Rovere, Rita; Shemy, Ahmed; Voet, Arnout; Eelen, Guy; Dewerchin, Mieke; Tait, Stephen W. G.; Ghesquière, Bart; Bootman, Martin D.; Bultynck, Geert

Source

Cell Death & Disease; Sep2023, Vol. 14 Issue 9, p1-17, 17p

Subject

Language

ISSN

20414889

Online Access

Full Text (ProQuest Central) Web of Science JCR 저널정보 Scopus Find it@PNU

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