부산대학교 도서관

Background: Implantable cardioverter‐defibrillators (ICDs) provide clinically significant therapy for the prevention of sudden cardiac death. This study aimed to characterize the substernal space using computed tomography (CT) in patients with and without prior midline sternotomy to investigate the feasibility of substernal ICD lead implantation in post‐sternotomy patients. Methods: High‐quality electrocardiogram‐gated CT images from 100 patients (71% male, average body mass index 23.5 ± 2.9) were retrospectively collected, including 50 patients with prior midline sternotomy (S‐group) and 50 patients with no prior sternotomy (NS‐group). Distances were measured from the retrosternal surface to the epicardial surface of the heart and segmented into four regions from the xiphoid tip and superiorly along the sternum. Results: Results generally showed a measurable but narrower average sternum‐to‐heart distance in the prior sternotomy group compared to the non‐sternotomy group in all four regions (p <.05). In the S‐group, the sternum‐to‐heart distances across all regions ranged from 0 to 32.0 mm, while in the NS‐group, the distances ranged from 0 to 39.9 mm. Conclusion: Small but measurable separations between the heart and sternum were observed in patients with prior sternotomy, particularly near the xiphoid region, indicating the potential viability of extravascular substernal ICD lead implantation in post‐sternotomy patients. [ABSTRACT FROM AUTHOR]