부산대학교 도서관

Of 749 women with baseline data on TE, 41 (5.5%) had a TE at the time of PPCM diagnosis ( I Figure i 1A), 1.1% had a stroke, 1.7% an arterial TE and 4.2% a venous TE. The most common causes of death were HF and stroke (each accounting for 40% of deaths) in women with TE compared with HF in women without TE (41% due to HF, 33% sudden). Peripartum cardiomyopathy (PPCM) is a form of heart failure (HF) that develops towards the end of pregnancy or within the first months after delivery.[1] Rates of thromboembolism in PPCM are reportedly higher than in many other cardiomyopathies.[2] In the United States, thromboembolism was the most common serious complication in PPCM, occurring in 6.6% of affected women.[3] In the multinational European Society of Cardiology (ESC) EURObservational Research Programme (EORP) PPCM registry, 5% of patients had a thromboembolic event (TE) during the index hospitalization.[4] The peripartum period is a hypercoagulative phase, an evolutionary remnant to minimize postpartum haemorrhage.[5] The combination of left ventricular (LV) dilatation, endothelial injury, immobility, and postpartum hypercoagulable state, may explain the high prevalence of TE in women with PPCM. [Extracted from the article]