학술논문

Infection‐induced seroconversion and seroprevalence of SARS‐CoV‐2 among a cohort of children and youth in Montreal, Canada.
Document Type
Article
Source
Influenza & Other Respiratory Viruses. Aug2023, Vol. 17 Issue 8, p1-6. 6p.
Subject
*SEROCONVERSION
*SEROPREVALENCE
*SARS-CoV-2
*RACIAL minorities
*AGE groups
*ACQUISITION of data
Language
ISSN
1750-2640
Abstract
The EnCORE study is a prospective serology study of SARS‐CoV‐2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May–October 2022), we estimated SARS‐CoV‐2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9–12 times more likely to seroconvert during the early Omicron‐dominant period compared to pre‐Omicron rounds. Unlike the pre‐Omicron rounds, the adjusted rate of seroconversion among 2‐ to 4‐year‐olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status. [ABSTRACT FROM AUTHOR]