학술논문
Post‐COVID‐19 vaccination Guillain–Barré syndrome with sensory ataxia, gaze‐evoked nystagmus, mental‐status change and positive pathological reflex.
Document Type
Article
Source
Subject
*SENSORY ataxia
*GUILLAIN-Barre syndrome
*COVID-19
*COVID-19 pandemic
*PATHOLOGICAL physiology
*BENIGN paroxysmal positional vertigo
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Language
ISSN
1759-1961
Abstract
Background: Various neurological disorders have been reported after vaccination against coronavirus disease 2019, one of which is Guillain–Barré Syndrome (GBS). Case Presentation: We report a case of a 73‐year‐old woman who developed GBS and extra‐GBS manifestations 19 days after the second dose of BNT162b2 mRNA vaccine. She presented lower limb predominant muscle weakness and loss of tendon reflexes. Nerve conduction study showed acute motor and sensory axonal neuropathy. In addition, she developed notable deep sensory ataxia, and showed positive pathological reflex, gaze‐evoked nystagmus and altered consciousness, which suggested brainstem involvement. Conclusions: This is the first coronavirus disease 2019 vaccine‐related GBS complicated with such central nervous system manifestations. [ABSTRACT FROM AUTHOR]