학술논문

Beyond transcription: compelling open questions in plant RNA biology.
Document Type
Article
Source
Plant Cell. Jun2023, Vol. 35 Issue 6, p1626-1653. 28p.
Subject
*PLANT RNA
*ALTERNATIVE RNA splicing
*LINCRNA
*RNA interference
*NON-coding RNA
*SMALL nuclear RNA
Language
ISSN
1040-4651
Abstract
The study of RNAs has become one of the most influential research fields in contemporary biology and biomedicine. In the last few years, new sequencing technologies have produced an explosion of new and exciting discoveries in the field but have also given rise to many open questions. Defining these questions, together with old, long-standing gaps in our knowledge, is the spirit of this article. The breadth of topics within RNA biology research is vast, and every aspect of the biology of these molecules contains countless exciting open questions. Here, we asked 12 groups to discuss their most compelling question among some plant RNA biology topics. The following vignettes cover RNA alternative splicing; RNA dynamics; RNA translation; RNA structures; R-loops; epitranscriptomics; long non-coding RNAs; small RNA production and their functions in crops; small RNAs during gametogenesis and in cross-kingdom RNA interference; and RNA-directed DNA methylation. In each section, we will present the current state-of-the-art in plant RNA biology research before asking the questions that will surely motivate future discoveries in the field. We hope this article will spark a debate about the future perspective on RNA biology and provoke novel reflections in the reader. [ABSTRACT FROM AUTHOR]