학술논문

Impacts of Environmental Pollution on Brain Tumorigenesis.
Document Type
Article
Source
International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 5, p5045. 17p.
Subject
*POLLUTION
*ENVIRONMENTAL risk
*NEOPLASTIC cell transformation
*BRAIN tumors
*BIOMOLECULES
DEVELOPED countries
Language
ISSN
1661-6596
Abstract
Pollutants consist of several components, known as direct or indirect mutagens, that can be associated with the risk of tumorigenesis. The increased incidence of brain tumors, observed more frequently in industrialized countries, has generated a deeper interest in examining different pollutants that could be found in food, air, or water supply. These compounds, due to their chemical nature, alter the activity of biological molecules naturally found in the body. The bioaccumulation leads to harmful effects for humans, increasing the risk of the onset of several pathologies, including cancer. Environmental components often combine with other risk factors, such as the individual genetic component, which increases the chance of developing cancer. The objective of this review is to discuss the impact of environmental carcinogens on modulating the risk of brain tumorigenesis, focusing our attention on certain categories of pollutants and their sources. [ABSTRACT FROM AUTHOR]