학술논문
Safety and efficacy of combinatorial therapy utilizing myeloablative conditioning and autologous stem cell transplantation, targeted immunotherapy, and reduced intensity conditioning and allogeneic stem cell transplantation in children, adolescents, and young adults with relapsed/refractory mature B-cell non-Hodgkin lymphoma
Document Type
Article
Author
Source
Subject
*STEM cell transplantation
*YOUNG adults
*NON-Hodgkin's lymphoma
*CORD blood transplantation
*TEENAGERS
*
*
*
*
Language
ISSN
1042-8194
Abstract
To the Editor: More than half of the non-Hodgkin lymphomas (NHL) occurring in children, adolescents, and young adults (CAYA) in North America and Europe are comprised mature B-cell NHL (B-NHL) [[1]]. Salvage reinduction regimens resulted in 6/12 (50%) patients achieving a CR, 5/12 (41.6%) patients attaining a PR and 1/12 (8.3%) patients with progressive disease (PD). Post MAC autoSCT 7/12 patients (58%) were in a CR, two patients (16.7%) were in a PR, two patients (16.7%) had stable disease and one patient (8.3%) had PD. Amongst the three patients with diffuse large B-cell lymphoma one was in CR, one had stable disease and one had PD post MAC autoSCT. [Extracted from the article]