학술논문

Case of Suspected SARS-CoV-2 Vaccine-induced Immune Thrombotic Thrombocytopenia: Dilemma for Organ Donation.
Document Type
Article
Source
Indian Journal of Critical Care Medicine. Apr2022, Vol. 26 Issue 4, p516-519. 4p. 1 Color Photograph, 1 Black and White Photograph, 1 Chart, 1 Graph.
Subject
*BRAIN death
*SINUS thrombosis
*COVID-19 vaccines
*THROMBOPENIC purpura
*EVIDENCE-based medicine
*TREATMENT effectiveness
*ORGAN donation
*DISEASE complications
Language
ISSN
0972-5229
Abstract
Several vaccines were developed and rolled out at an unprecedented rate in response to the coronavirus disease-2019 (COVID-19) pandemic. Most vaccines approved globally by WHO for emergency use to combat the pandemic were deemed remarkably effective and safe. Despite the safety, rare incidences of vaccine-induced thrombosis and thrombocytopenia (VITT), sometimes known as vaccine-induced prothrombotic thrombocytopenia (VIPIT), have been reported. We report a case of young female with prothrombotic conditions and suspected VITT who developed catastrophic cerebral venous sinus thrombosis (CVST) and progressed to brain death. We highlight hurdles of organ retrieval from a brain-dead patient with suspected SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia. There is limited data and lack of substantial evidence regarding transplantation of organs from brain-dead patients with suspected VITT. [ABSTRACT FROM AUTHOR]