부산대학교 도서관

This study aimed to estimate the prognostic factors, long-term outcomes, and surgical strategies for parasagittal meningioma (PSM) and provide a better understanding of surgical experience. Patients (n = 1438) who underwent surgery for meningioma between January 2012 and January 2013 were enrolled in a database. We then identified 165 patients with PSM based on this database. Of the 165 patients with identified PSMs, 103 were female and 62 were male, with a mean age of 49 years. Univariate analysis revealed that male sex (p =.002), non-World Health Organization (WHO) grade I meningioma (p <.001), treatment history (p =.006), surgical time more than 232 minutes (p =.006), and intraoperative bleeding > 300mL3 (p =.019) were associated with decreased progression-free survival (PFS). Multivariate analysis revealed that sex (hazards ratio [HR] = 3.836, 95% confidence interval [CI] = 1.364–10.794; p =.011], tumour grade (HR = 8.479, 95% CI = 3.234–22.230; p <.001), and surgical time (HR = 3.710, 95% CI = 1.057–13.023; p =.041) were independent factors for PFS. Patients with Simpson grade I-II (p =.015), no-treatment history (p =.006), tumour size < 3cm (p =.005), surgical time < 232 minutes (p =.019), intraoperative bleeding < 300mL3 (p <.001), or WHO grade I meningioma (p =.002) had better follow-up conditions. Surgery was an effective treatment for PSM, and at the time of final follow-up, patients who received aggressive resection had a substantially higher Karnofsky performance scale score. [ABSTRACT FROM AUTHOR]