부산대학교 도서관

Colon diverticulae may rupture due to increased intraluminal pressure in combination with several other factors, such as corticosteroid or nonsteroidal anti-inflammatory drugs administration, smoking and alcohol consumption. Cortisone is considered a well-known risk factor for diverticular perforation in neurosurgical patients. We report a case of a 73-year-old male patient, with a known past medical history of fascial melanoma treated with wide local excision and two brain metastases managed with methylprednisolone, who presented with clinical and radiological diverticular perforation. At laparotomy a fecal peritonitis and multiple diverticulae ruptures of the descending and sigmoid colon was found (Hinchey stage D). A Hartmann's procedure was undertaken, but the patient unfortunately died from septic sequelae on the 13th postoperative day. [ABSTRACT FROM AUTHOR]