학술논문
Atypical HUS Triggered by COVID-19: A Case Report.
Document Type
Article
Author
Source
Subject
*COVID-19
*BIOPSY
*KIDNEY transplantation
*HEMOLYTIC-uremic syndrome
*PLASMAPHERESIS
*LIVER transplantation
*DISEASE risk factors
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Language
ISSN
0971-4065
Abstract
We hereby present a case of an atypical hemolytic uremic syndrome (aHUS) precipitated by coronavirus disease 2019 (COVID-19). A 26-year-old male was diagnosed with COVID-19 and acute kidney injury. His kidney biopsy was suggestive of thrombotic microangiopathy. Five sessions of plasmapheresis were done but were discontinued in view of nonrecovery of kidney function. He was then referred for a kidney transplant. On genetic analysis, he was found to have mutations in the complement system (CFHR1 and CFHR3), which suggested this was a case of aHUS precipitated by COVID-19. In view of the high risk of recurrence of the primary disease in live-related kidney donor transplantation, he was advised for simultaneous liver and kidney transplants. [ABSTRACT FROM AUTHOR]