학술논문

Efficacy of Brucella abortus S19 and RB51 vaccine strains: A systematic review and meta‐analysis.
Document Type
Article
Source
Transboundary & Emerging Diseases. Jul2022, Vol. 69 Issue 4, p1670-1673. 4p.
Subject
*BRUCELLA abortus
*VETERINARY vaccines
*VACCINATION complications
*VACCINES
*MISCARRIAGE
Language
ISSN
1865-1674
Abstract
Both S19 and RB51 can persist for 2-3 months in 4-6 months old vaccinated heifers and for longer times in adults (replacement heifers vaccinated with RB51 can even excrete this vaccine during the first parturition) (Olsen et al., 1999; Plommet & Plommet, 1976). In brucellosis, perhaps more than in other infectious diseases, the rule applies that "a bad vaccine is worse than no vaccine" because of the false sense of security that bad vaccines convey (Moreno, 2014). Comparing results obtained with different bacteriological methods, cattle breeds, ages, vaccine doses, vaccination routes, vaccination-challenge intervals, and different bacterial strains is a rather complicated process that cannot be simplified to obtain concrete figures for doses of vaccines. Dear Editor, Bovine brucellosis caused by I B. abortus i or less often by I B. melitensis i is an infectious disease difficult to eradicate and a major zoonosis in resource-limited settings. [Extracted from the article]