학술논문

Circulation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India.
Document Type
Article
Source
Clinical Infectious Diseases. 6/15/2022, Vol. 74 Issue 12, p2234-2237. 4p.
Subject
*GENETIC mutation
*FLUOROQUINOLONES
*TYPHOID fever
*THIRD generation cephalosporins
*SALMONELLA
*BETA lactamases
*DRUG resistance in microorganisms
*MICROBIAL sensitivity tests
Language
ISSN
1058-4838
Abstract
We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene bla SHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance. [ABSTRACT FROM AUTHOR]