학술논문
Monitoring occurrence of SARS-CoV-2 in school populations: A wastewater-based approach.
Document Type
Article
Author
Castro-Gutierrez, Victor; Hassard, Francis; Vu, Milan; Leitao, Rodrigo; Burczynska, Beata; Wildeboer, Dirk; Stanton, Isobel; Rahimzadeh, Shadi; Baio, Gianluca; Garelick, Hemda; Hofman, Jan; Kasprzyk-Hordern, Barbara; Kwiatkowska, Rachel; Majeed, Azeem; Priest, Sally; Grimsley, Jasmine; Lundy, Lian; Singer, Andrew C.; Di Cesare, Mariachiara
Source
Subject
*SARS-CoV-2
*ECONOMIC impact
*GENE frequency
*FURTHER education (Great Britain)
*COVID-19 pandemic
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Language
ISSN
1932-6203
Abstract
Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing. [ABSTRACT FROM AUTHOR]