학술논문
Matrix proteins plug a hole: How pericytes suppress blood brain barrier transcytosis.
Document Type
Article
Author
Source
Subject
*EXTRACELLULAR matrix proteins
*PERICYTES
*TRANSCYTOSIS
*ENDOTHELIAL cells
*BLOOD cells
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*
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Language
ISSN
0896-6273
Abstract
How is the brain so efficient at excluding proteins, drugs, and immune cells from the blood? In this issue of Neuron, Ayloo et al. (2022) find that an extracellular matrix protein secreted by CNS pericytes shuts down endocytic transport in blood brain barrier endothelial cells. [ABSTRACT FROM AUTHOR]