부산대학교 도서관

Trisomy 21 or Down syndrome is the most common chromosomal abnormality reported worldwide. The prevalence of infantile spasms was 3% in our population with Down syndrome, which is slightly higher than the median lifetime prevalence of 2.1% (range 0.4-12.8) of epileptic spasms recently reported.5 Studies focusing on treatments and outcomes of infantile spasms in cohorts with Down syndrome are lacking. Abbreviations ACTH Adrenocorticotropic hormone ICISS International Collaborative Infantile Spasms Study What this paper adds The prevalence of infantile spasms in Down syndrome was 3%. Vigabatrin was responsible for most ( I n i =10), followed by combination prednisolone and vigabatrin ( I n i =6), prednisolone ( I n i =4), sodium valproate ( I n i =2), and other ( I n i =3). [Extracted from the article]