부산대학교 도서관

Allele frequencies for these common, low-penetrance bladder cancer susceptibility SNPs are not substantially different among the bladder patients in these studies and the broader European population. 1 TableAssociations of bladder cancer risk single nucleotide polymorphisms and polygenic risk score with overall and disease-specific survival in the New Hampshire cohort (n = 273 non-muscle invasive and n = 43 muscle-invasive bladder cancer) and the UK Biobank cohort (n = 364 incident bladder cancer cases). Abbreviations GWAS genome-wide association study HR hazard ratio ICD International Statistical Classification of Diseases MIBC muscle-invasive bladder cancer NMIBC non-muscle-invasive bladder cancer PRS polygenic risk score SNP single nucleotide polymorphism TURBT transurethral resection of bladder tumour Each year 573 000 bladder cancer diagnoses and 212 000 bladder cancer-related deaths occur worldwide [1]. We found no association between bladder cancer susceptibility variants, individually or as a PRS, and overall survival or disease-specific survival after bladder cancer diagnosis (Table 1). [Extracted from the article]