학술논문

Hypervitaminosis D and Acute Interstitial Nephritis: Tale of Injections.
Document Type
Article
Source
Indian Journal of Nephrology. Jan/Feb2022, Vol. 32 Issue 1, p71-75. 5p.
Subject
*HYPERCALCEMIA
*SUBSTANCE abuse
*BUTTOCKS
*DEBRIDEMENT
*HYPERVITAMINOSIS
*INTERSTITIAL nephritis
*ABSCESSES
*VITAMIN D
*INTRAMUSCULAR injections
*PENTAZOCINE
*ABDOMINAL pain
*COMPUTED tomography
*CALCIUM
*CREATININE
Language
ISSN
0971-4065
Abstract
A 33-year-old man came with nausea, vomiting and abdominal pain due to hypercalcaemia and renal dysfunction following two doses of intramuscular vitamin D injections. Levels of vitamin D were repeatedly above 300 ng/ml over a period of 10 months. Whole-body PET CT scan revealed a thin-walled collection in the right gluteal region. The patient refused a surgical intervention for the same. After 7 months of follow-up, the abscess ruptured spontaneously and was then surgically debrided. At this point, a history of pentazocine addiction was uncovered. One month later, vitamin D levels began to fall along with improvement in serum calcium and creatinine. This case unravels a diagnostic odyssey which ended with a simple surgical debridement. We aim to highlight that vitamin D supplementation in 'megadoses' in the presence of active infection can have an exaggerated response and may take months to resolve. [ABSTRACT FROM AUTHOR]