학술논문
Ultrasensitive pathogen detection with a rolling circle amplification-empowered multiplex electrochemical DNA sensor.
Document Type
Article
Author
Source
Subject
*ELECTROCHEMICAL sensors
*BIOLOGICAL assay
*HOUGH transforms
*CIRCLE
*PATHOGENIC microorganisms
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Language
ISSN
1359-7345
Abstract
We report a highly sensitive and selective multiplex assay by empowering an electrochemical DNA sensor with isothermal rolling circle amplification. The assay could simultaneously detect and discriminate three common entero-pathogens in a single reaction, with femtomolar sensitivity. It is useful for field- or resource-limited settings. [ABSTRACT FROM AUTHOR]