학술논문
Relapse of Lymphangioleiomyomatosis Five Years after Bilateral-Lung Transplantation.
Document Type
Article
Author
Source
Subject
*BIOPSY
*RAPAMYCIN
*LUNG transplantation
*CANCER relapse
*LUNG tumors
*LYMPHATIC tumors
*DYSPNEA
*DISEASE relapse
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Language
ISSN
1029-2977
Abstract
Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease principally affecting women during childbearing years and eventually leading to progressive respiratory failure. Lung transplantation is a viable option for patients with end-stage disease. LAM-related complications remain common, but recurrence of LAM following allograft transplantation is rare. We present a 25-year-old woman who presented with progressive dyspnea five years after bilateral lung transplantation for end-stage LAM. Histological examination of transbronchial lung biopsy sample confirmed recurrent LAM. We changed cyclosporine to sirolimus and she is currently being considered for re-transplantation. [ABSTRACT FROM AUTHOR]