학술논문
Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016-2017.
Document Type
Journal Article
Author
Santiago, Gilberto A.; Kalinich, Chaney C.; Cruz-López, Fabiola; González, Glenda L.; Flores, Betzabel; Hentoff, Aaron; Charriez, Keyla N.; Fauver, Joseph R.; Adams, Laura E.; Sharp, Tyler M.; Black, Allison; Bedford, Trevor; Ellis, Esther; Ellis, Brett; Waterman, Steve H.; Paz-Bailey, Gabriela; Grubaugh, Nathan D.; Muñoz-Jordán2, Jorge L.; Muñoz-Jordán, Jorge L
Source
Subject
*ZIKA virus
*MOLECULAR evolution
*EPIDEMICS
*NUCLEOTIDE sequencing
*GENOMES
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Language
ISSN
1080-6040
Abstract
We reconstructed the 2016-2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic's origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns, and ≈10 months of cryptic transmission. [ABSTRACT FROM AUTHOR]